Clinical Compound
Library

Overview

Thymosin Beta-4 is a naturally occurring peptide present in almost all animal and human cells, with the highest concentrations found in blood platelets and wound fluid. It plays a vital role in tissue regeneration and injury repair.

Mechanism of Action

Functions as an actin-sequestering protein, regulating the cell cytoskeleton to promote cell migration (endothelial cells and keratinocytes) to the site of injury. Also downregulates inflammatory cytokines and promotes angiogenesis.

Potential Applications

Muscle tear repair, enhanced flexibility, cardiac tissue protection post-infarction, corneal healing, and reduction of scar tissue (fibrosis).

Research Summary

• Demonstrated dramatic acceleration of dermal wound healing and muscle regeneration in murine injury models.

Scientific Citations

• Goldstein, A. L., et al. (2012). Thymosin β4: actin-sequestering protein moonlights to repair injured tissues. Trends in Molecular Medicine, 18(5), 271–278.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C away from direct light. Stable for 30 days post-reconstitution.

Overview

BPC-157 is a 15-amino acid sequence derived from human gastric juice. Renowned for potent systemic healing properties, particularly concerning the gastrointestinal tract, tendons, ligaments, and nervous system.

Mechanism of Action

Upregulates early growth response protein 1 (EGR-1), promotes angiogenesis via VEGF expression, and modulates the nitric oxide (NO) system.

Potential Applications

Tendon and ligament repair, gut mucosal healing (Leaky Gut, IBD), neuroprotection, and systemic inflammation reduction.

Research Summary

• Demonstrated accelerated healing of transected Achilles tendons in rat models.

Scientific Citations

• Seiwerth, S., et al. (2018). BPC 157 and Standard Angiogenic Growth Factors. Current Pharmaceutical Design, 24(18), 1972–1989.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C away from direct light. Stable for 30 days post-reconstitution.

Overview

A synergistic blend of BPC-157 and Thymosin Beta-4. Considered the gold standard in peptide therapy for systemic healing, combining gastrointestinal and localized healing with accelerated cellular migration.

Mechanism of Action

BPC-157 rapidly builds new microvasculature and downregulates localized inflammation, while TB4 regulates actin to mobilize repair cells along the newly formed vascular networks directly to the injury site.

Potential Applications

Severe tendinopathy, ligament tears, post-surgical recovery, severe chronic joint pain, and systemic inflammatory modulation.

Research Summary

• Sports medicine applications show drastic reduction in recovery time for severe soft-tissue injuries when both peptides are administered concurrently compared to isolated therapy.

Scientific Citations

• Cross-referenced literature for BPC-157 angiogenesis and TB4 actin-sequestering mechanisms; blend efficacy supported by sports medicine clinical protocols.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for approximately 30 days post-reconstitution.

Overview

ARA-290 is a synthetic 11-amino acid peptide derived from erythropoietin (EPO). Unlike EPO, it does not stimulate red blood cell production, making it safe for daily use without cardiovascular risk.

Mechanism of Action

Selectively binds to the Innate Repair Receptor (IRR), initiating a cascade that suppresses inflammatory cytokines, prevents tissue damage, and promotes repair of small nerve fibers.

Potential Applications

Small fiber neuropathy, sarcoidosis, diabetic neuropathy, fibromyalgia, and chronic neuropathic pain conditions.

Research Summary

• Demonstrated significant increases in corneal nerve fiber density and significant reduction in pain scores in patients with sarcoidosis-associated neuropathy.

Scientific Citations

• Dahan, A., et al. (2013). ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss. Molecular Medicine, 19(1), 334–345.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C away from direct light. Stable for 30 days post-reconstitution.

Overview

KLOW is a highly potent, synergistic 4-peptide blend consisting of BPC-157, TB4, GHK-Cu, and KPV. Designed for maximum regenerative capacity, addressing both massive systemic inflammation and structural tissue rebuilding.

Mechanism of Action

Combines BPC-157's angiogenesis, TB4's cellular migration (actin regulation), GHK-Cu's collagen and elastin synthesis, and KPV's heavy NF-κB inhibition for a dedicated systemic anti-inflammatory effect.

Potential Applications

Post-surgical recovery (plastic surgery, orthopedic), severe chronic inflammatory conditions, severe joint/muscle injury, and total-body regenerative therapies.

Research Summary

• Extensively utilized in off-label post-surgical and regenerative clinic protocols for accelerating recovery timelines, reducing swelling, and promoting rapid tissue stabilization.

Scientific Citations

• Proprietary blend: clinical application relies on the individual established literature for BPC-157, TB4, GHK-Cu, and KPV.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for approximately 30 days post-reconstitution.

Overview

Cartalax (AED, Ala-Glu-Asp) is a synthetic Khavinson tripeptide acting as a bioregulator targeting cartilage and connective tissues. Synthesized based on the sequence found in type XI collagen.

Mechanism of Action

Binds to DNA histones to upregulate gene expression specific to chondrocytes and fibroblasts, stimulating synthesis of type II collagen and proteoglycans while inhibiting matrix degradation.

Potential Applications

Osteoarthritis, rheumatoid arthritis, joint degeneration, spinal issues, and preventative joint health in aging and athletic populations.

Research Summary

• In vitro and animal models demonstrate significant regulation of cellular renewal in cartilage fibroblasts and a strong regenerative effect on aging tissue.

Scientific Citations

• Khavinson, V. K., et al. (2016). Short Peptides Regulate Gene Expression. Bulletin of Experimental Biology and Medicine, 162(2), 288–292.

Handling & Storage

Keep capsules at room temperature. Lyophilized powder should be refrigerated at 2–8°C post-reconstitution.

Overview

Retatrutide is a revolutionary single-molecule tri-agonist, considered the next generation of metabolic therapies beyond Tirzepatide, targeting aggressive weight loss and liver fat reduction.

Mechanism of Action

Simultaneously agonizes three metabolic receptors: GLP-1, GIP, and the Glucagon receptor (GCGR). This triple action vastly increases energy expenditure while suppressing appetite.

Potential Applications

Severe obesity, non-alcoholic fatty liver disease (NAFLD), and Type 2 diabetes management.

Research Summary

• Phase 2 trials showed an unprecedented 24.2% average body weight reduction over 48 weeks — the most potent pharmacological weight loss agent recorded to date.

Scientific Citations

• Jastreboff, A. M., et al. (2023). Triple-Hormone-Receptor Agonist Retatrutide for Obesity. NEJM, 389(6), 514–526.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for up to 30 days post-reconstitution.

Overview

Tirzepatide is a dual-targeted peptide (marketed as Mounjaro/Zepbound) used for chronic weight management and glycemic control. Functions as a dual GIP and GLP-1 receptor agonist.

Mechanism of Action

Synergistically slows gastric emptying, signals satiety to the brain, and enhances insulin secretion while decreasing glucagon.

Potential Applications

Obesity, chronic weight management, Type 2 diabetes, and metabolic syndrome.

Research Summary

• SURMOUNT-1 trials demonstrated up to 22.5% body weight reduction over 72 weeks in obese adults without diabetes.

Scientific Citations

• Jastreboff, A. M., et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. NEJM, 387(3), 205–216.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for 30 days post-reconstitution.

Overview

AOD9604 is a modified fragment of HGH (C-terminal amino acids 177–191), designed to emulate HGH's fat-burning effects without stimulating growth or affecting blood sugar.

Mechanism of Action

Stimulates lipolysis (breakdown of fat) and inhibits lipogenesis directly at the adipose tissue level, without the adverse effects of full-sequence HGH.

Potential Applications

Fat loss, metabolic regulation, and osteoarthritis support (especially when injected intra-articularly).

Research Summary

• Strong fat-reducing capacity in animal and human models without insulin resistance or IGF-1 elevation.

Scientific Citations

• Heffernan, M., et al. (2001). The Effects of Human GH and Its Lipolytic Fragment (AOD9604) on Lipid Metabolism. Endocrinology, 142(12), 5182–5189.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for 30 days post-reconstitution.

Overview

MOTS-c is a 16-amino acid mitochondrial-derived peptide acting as a crucial regulator of metabolic homeostasis and physical capacity. Functions as an exercise mimetic at the cellular level.

Mechanism of Action

Targets skeletal muscle to enhance insulin sensitivity and promote glucose utilization by activating the AMPK pathway.

Potential Applications

Diet-induced obesity reversal, Type 2 diabetes management, exercise performance enhancement, and metabolic optimization.

Research Summary

• Completely prevented high-fat diet-induced obesity and insulin resistance in murine models.
• Enhanced skeletal muscle glucose uptake without stimulating endogenous insulin production.

Scientific Citations

• Lee, C., et al. (2015). The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis. Cell Metabolism, 21(3), 443–454.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Highly sensitive; administer immediately after drawing.

Overview

SS-31 is a highly specialized, cell-permeable peptide that targets the inner mitochondrial membrane, directly protecting mitochondrial function against oxidative stress.

Mechanism of Action

Binds selectively to cardiolipin on the inner mitochondrial membrane, restoring structural integrity, optimizing electron transport, and massively reducing reactive oxygen species (ROS) production.

Potential Applications

Heart failure, acute kidney injury, neurodegenerative diseases, muscle weakness, and profound anti-aging via mitochondrial rescue.

Research Summary

• Demonstrated ability to reverse age-related mitochondrial dysfunction in skeletal muscle, restoring youthful ATP production and reducing oxidative damage.

Scientific Citations

• Szeto, H. H. (2014). First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. British Journal of Pharmacology, 171(8), 2029–2050.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C away from direct light. Stable for 30 days post-reconstitution.

Overview

5-Amino 1-methylquinolinium (5-Amino 1MQ) is a small molecule that heavily influences cellular energy metabolism and obesity without acting on the central nervous system.

Mechanism of Action

Inhibits NNMT (Nicotinamide N-methyltransferase), an enzyme highly active in fat tissue. Inhibiting NNMT prevents NAD+ depletion, pushing the cell into extreme fat oxidation and mitochondrial biogenesis.

Potential Applications

Targeted fat loss, muscle mass preservation during calorie restriction, and reversal of diet-induced obesity.

Research Summary

• Mice treated with NNMT inhibitors showed a 30% reduction in white adipose tissue volume without altering food intake.

Scientific Citations

• Neelakantan, H., et al. (2018). Small molecule NNMT inhibitor activates senescent muscle stem cells. Biochemical Pharmacology, 153, 11–19.

Handling & Storage

Store capsules in a cool, dry place away from direct sunlight at room temperature.

Overview

Oxytocin is a mammalian neurohypophysial hormone involved in social bonding, sexual reproduction, and stress regulation. In clinical optimization, utilized for emotional and stress management.

Mechanism of Action

Binds to the oxytocin receptor (OXTR), a G-protein-coupled receptor, modulating the amygdala to reduce fear signaling and decreasing cortisol levels.

Potential Applications

Social anxiety reduction, libido enhancement, PTSD therapy support, autism spectrum behavioral modulation, and pain perception management.

Research Summary

• Intranasal administration has been shown to increase trust, empathy, and positive social interactions while dampening stress responses in human subjects.

Scientific Citations

• Kosfeld, M., et al. (2005). Oxytocin increases trust in humans. Nature, 435(7042), 673–676.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Highly sensitive to temperature; use within 30 days post-reconstitution.

Overview

PT-141 is a synthetic peptide analog of alpha-MSH. Unlike typical sexual dysfunction treatments that act on the vascular system, PT-141 works directly on the central nervous system to induce sexual arousal.

Mechanism of Action

Acts as an agonist at melanocortin receptors (MC3R and MC4R) in the brain, directly stimulating the pathways responsible for sexual desire and arousal in both men and women.

Potential Applications

Erectile dysfunction (especially psychogenic ED), Hypoactive Sexual Desire Disorder (HSDD) in women, and general libido enhancement.

Research Summary

• FDA-approved under the brand name Vyleesi for generalized HSDD in premenopausal women. Demonstrates strong efficacy in men unresponsive to Viagra or Cialis.

Scientific Citations

• Kingsberg, S. A., et al. (2019). Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder. Obstetrics & Gynecology, 134(5), 899–908.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for up to 30 days post-reconstitution.

Overview

Kisspeptin is a neuropeptide that acts as the upstream "master switch" for human reproductive function and puberty onset, regulating the hypothalamic-pituitary-gonadal (HPG) axis.

Mechanism of Action

Binds to the KISS1 receptor in the hypothalamus, powerfully stimulating release of GnRH, which in turn triggers pulsatile release of LH and FSH.

Potential Applications

Hypogonadism, restoring natural testosterone production, increasing fertility, enhancing libido, and restarting the HPG axis post-steroid use (PCT).

Research Summary

• Demonstrated robust ability to stimulate LH pulses and increase serum testosterone in men, circumventing the negative feedback loop often caused by exogenous hormone administration.

Scientific Citations

• Dhillo, W. S., et al. (2005). Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males. J Clinical Endocrinology & Metabolism, 90(12), 6609–6615.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for up to 30 days post-reconstitution.

Overview

HCG is a naturally occurring polypeptide hormone. In clinical optimization, utilized by males to maintain testicular function and by both genders for metabolic protocols.

Mechanism of Action

Mimics LH in the body. In males, directly stimulates Leydig cells in the testes to produce endogenous testosterone, preventing testicular atrophy during exogenous testosterone therapy.

Potential Applications

TRT adjunct to preserve fertility and testicular size, hypogonadism, and medically supervised weight loss protocols.

Research Summary

• Proven universally effective in maintaining intra-testicular testosterone levels and spermatogenesis in males undergoing long-term androgen therapy.

Scientific Citations

• Coviello, A. D., et al. (2005). Low-dose HCG maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression. J Clinical Endocrinology & Metabolism, 90(5), 2595–2602.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C immediately. Highly fragile; degrades quickly if not refrigerated. Stable for roughly 30 days.

Overview

A highly effective combined formulation of CJC-1295 without DAC (Mod GRF 1-29) and Ipamorelin. Considered the safest growth hormone-releasing blend available for anti-aging and wellness protocols.

Mechanism of Action

CJC-1295 without DAC dictates the strength of the GH pulse, while Ipamorelin dictates timing and suppresses somatostatin — mimicking the body's natural pulsatile GH release.

Potential Applications

Anti-aging, sleep improvement, mild fat loss, muscle recovery, and overall vitality without pituitary exhaustion.

Research Summary

• Proven to safely elevate IGF-1 and GH output in humans without elevating stress hormones like cortisol or prolactin.

Scientific Citations

• Raun, K., et al. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology, 139(5), 552–561.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for 30 days post-reconstitution.

Overview

A potent synergistic combination of Tesamorelin (GHRH analog) and Ipamorelin (GHSR agonist). Maximizes natural growth hormone pulses without elevating cortisol or prolactin levels.

Mechanism of Action

Tesamorelin prompts the pituitary to release GH, while Ipamorelin suppresses somatostatin. Together, they amplify the biological GH pulse via dual-pathway stimulation.

Potential Applications

Rapid visceral fat reduction, lean muscle preservation, skin elasticity improvement, and accelerated injury recovery.

Research Summary

• Dual-pathway stimulation is exponentially more effective at raising IGF-1 and GH levels over 24 hours compared to either peptide acting alone.

Scientific Citations

• Cross-referenced literature for Tesamorelin's lipolytic effects and Ipamorelin's selective GH release profile.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for 30 days post-reconstitution.

Overview

Tesamorelin is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH), uniquely powerful in its ability to target and reduce visceral adipose tissue.

Mechanism of Action

Binds to GHRH receptors in the anterior pituitary, stimulating a robust, physiological pulse of growth hormone which heavily regulates lipid metabolism and lipolysis.

Potential Applications

Reduction of visceral fat, improvement of lipid profiles, mild cognitive enhancement in older adults, and HIV-associated lipodystrophy (FDA-approved indication).

Research Summary

• Reduced visceral adipose tissue by up to 18% in clinical trials without altering systemic insulin resistance.

Scientific Citations

• Falutz, J., et al. (2007). Metabolic effects of a growth hormone-releasing factor in patients with HIV. NEJM, 357(23), 2359–2370.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for 30 days post-reconstitution.

Overview

Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from Epithalamin, a polypeptide secreted by the pineal gland. Renowned for its life-extension, anti-aging, and circadian rhythm-regulating properties.

Mechanism of Action

Activates the telomerase enzyme, facilitating elongation of telomeres at chromosome ends. Also regulates melatonin production by the pineal gland, restoring circadian rhythms.

Potential Applications

Cellular anti-aging, sleep normalization, immune system support in the elderly, and potential suppression of tumor growth.

Research Summary

• Demonstrated significant extension of lifespan and normalization of melatonin-cortisol circadian cycles in aging animal cohorts.

Scientific Citations

• Khavinson, V. Kh. (2002). Peptides and Ageing. Neuroendocrinology Letters, 23(Suppl 3), 11–144.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for up to 30 days post-reconstitution.

Overview

DSIP is a naturally occurring neuropeptide widely recognized for its ability to promote slow-wave (delta) sleep and modulate stress. Discovered in the brain blood of rabbits during induced sleep.

Mechanism of Action

Modulates the activity of GABAergic, glutamatergic, and noradrenergic systems, reducing corticotropin-releasing factor (CRF) and stabilizing the central nervous system.

Potential Applications

Insomnia management, chronic pain syndrome modulation, stress/cortisol reduction, and withdrawal symptom mitigation.

Research Summary

• Shown to normalize sleep architecture in humans suffering from insomnia without causing the grogginess typical of pharmaceutical sedatives.

Scientific Citations

• Kovalzon, V. M., & Strekalova, T. V. (2006). Delta sleep-inducing peptide (DSIP): a still unresolved riddle. Journal of Neurochemistry, 97(2), 303–309.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for 30 days post-reconstitution.

Overview

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in every living cell and is essential for hundreds of metabolic reactions. It exists in two interconvertible forms: NAD+ (oxidized) and NADH (reduced). Cellular NAD+ levels decline significantly with age — by as much as 50% between ages 40 and 60 — and this decline has been associated with metabolic dysfunction, neurodegeneration, and accelerated aging. NAD+ replenishment has become a major focus of longevity and healthy aging research.

Mechanism of Action

Acts as a critical electron carrier within the mitochondrial electron transport chain, enabling the conversion of nutrients into ATP for cellular energy production. NAD+ also serves as an essential substrate for sirtuins (SIRT1–7), which regulate gene expression, inflammation, and longevity pathways; PARP enzymes, which facilitate DNA repair; and CD38/CD157 enzymes involved in calcium signaling and immune function. Replenishing intracellular NAD+ levels supports mitochondrial biogenesis, genomic stability, cellular stress resistance, and overall metabolic health.

Potential Applications

Age-related energy decline, mitochondrial dysfunction, neurodegenerative disorders (including Parkinson's and Alzheimer's disease research), metabolic syndrome, cognitive support, cardiovascular health, chronic fatigue, healthy aging, and recovery protocols for alcohol and substance dependency.

Research Summary

• Preclinical studies have demonstrated that NAD+ restoration through precursor supplementation improves mitochondrial function, activates sirtuin signaling, and extends lifespan across multiple animal models.
• Human clinical studies involving NMN and NR have shown significant increases in circulating NAD+ levels, along with improvements in muscle function, insulin sensitivity, inflammatory biomarkers, and selected cognitive measures in older adults.
• IV NAD+ infusion is also utilized in clinical settings for addiction recovery and chronic fatigue, with reported benefits in withdrawal management and energy restoration.

Scientific Citations

• Yoshino, J., et al. (2018). NAD+ intermediates: The biology and therapeutic potential of NMN and NR. Cell Metabolism, 27(3), 513–528.
• Rajman, L., et al. (2018). Therapeutic potential of NAD-boosting molecules. Cell Metabolism, 27(3), 529–547.

Handling & Storage

Available as intravenous (IV) infusion (typically 250–1000mg over 1–4 hours), subcutaneous injection, intranasal spray, or sublingual tablet; oral supplementation commonly uses precursors such as NMN or NR, converted to NAD+ intracellularly. IV solutions are sensitive to heat and light — store at 2–8°C and administer promptly. Lyophilized powder: reconstitute with sterile saline or sterile water and use within 24 hours. Oral NMN/NR should be stored at room temperature in airtight, light-protective packaging. Do not freeze reconstituted solutions.

Overview

KPV is a naturally occurring tripeptide derived from the C-terminal region of alpha-MSH. A highly potent systemic and localized anti-inflammatory agent.

Mechanism of Action

Inhibits NF-κB, a central transcription factor responsible for inflammatory gene expression, effectively halting the inflammatory cascade inside the cell without immunosuppression.

Potential Applications

Inflammatory Bowel Disease (IBD), ulcerative colitis, psoriasis, allergic asthma, and localized skin inflammation.

Research Summary

• Significantly reduced mucosal damage and inflammatory markers in murine models of experimentally induced colitis.

Scientific Citations

• Dalmasso, G., et al. (2008). The anti-inflammatory peptide KPV down-regulates NF-κB and MAP kinase pathways. American Journal of Physiology-GI and Liver Physiology, 294(1), G52–G60.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for 30 days post-reconstitution.

Overview

Thymosin Alpha-1 is an endogenous peptide secreted by the thymus gland. Acts as a primary modulator of the immune system, essential for restoring immune function and regulating T-cell maturation.

Mechanism of Action

Stimulates the maturation of T-cells (CD4+ and CD8+), enhances the function of dendritic cells, and modulates the release of cytokines like Interferon-alpha and IL-2 to optimize immune responses.

Potential Applications

Chronic viral infections (Hepatitis B/C, Lyme disease, Epstein-Barr), autoimmune disease modulation, and as an adjuvant in vaccine response and cancer therapies.

Research Summary

• Extensively studied and approved in over 35 countries for the treatment of viral hepatitis and as an immune enhancer in immunocompromised patients.

Scientific Citations

• Goldstein, A. L., & Badamchian, M. (2004). Thymosins: chemistry and biological properties in health and disease. Expert Opinion on Biological Therapy, 4(4), 559–573.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for 30 days post-reconstitution.

Overview

Semax is a synthetic heptapeptide analog of ACTH 4-10. The N-Acetyl version is chemically modified to cross the blood-brain barrier more efficiently and resist enzymatic degradation, providing robust cognitive benefits.

Mechanism of Action

Dramatically increases expression of BDNF and NGF in the hippocampus and basal forebrain. Also modulates dopaminergic and serotonergic signaling.

Potential Applications

ADHD management, cognitive enhancement, stroke recovery, neuroprotection against oxidative stress, and memory consolidation.

Research Summary

• Demonstrated a 500% rapid increase in BDNF levels in animal models, leading to enhanced learning acquisition and prevention of hypoxic brain damage.

Scientific Citations

• Dolotov, O. V., et al. (2006). Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression. Brain Research, 1117(1), 54–60.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for 30 days post-reconstitution.

Overview

Selank is a synthetic analog of the immunomodulatory peptide Tuftsin. The N-Acetyl version increases stability and blood-brain barrier permeability. Primarily used as a potent, non-sedating anxiolytic.

Mechanism of Action

Modulates expression of IL-6 and balances the degradation of enkephalins in the blood. Also upregulates BDNF and affects GABAergic signaling.

Potential Applications

Generalized anxiety disorder, acute stress reduction, immune system modulation, and mood stabilization without the cognitive dulling of benzodiazepines.

Research Summary

• Proved equally effective as standard anxiolytics in treating generalized anxiety, with a significantly superior safety profile and no withdrawal symptoms.

Scientific Citations

• Uchakina, O. N., et al. (2008). Immunomodulatory effects of selank in patients with anxiety-asthenic disorders. Zhurnal Nevrologii i Psikhiatrii, 108(5), 71–75.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for 30 days post-reconstitution.

Overview

Adamax is a novel synthetic peptide analogue built on the backbone of Semax, extended with an Ala-Gly dipeptide with N-terminal acetylation and C-terminal amidation for improved enzymatic resistance and plasma half-life.

Mechanism of Action

Upregulates BDNF and NGF, activating TrkB receptor signaling pathways involved in synaptic plasticity, neuronal survival, and long-term potentiation. Terminal modifications provide superior metabolic stability versus standard Semax.

Potential Applications

Cognitive enhancement (memory, focus, learning), neuroprotection, recovery following neurological injury or ischemia, anxiety reduction, and prolonged neurotrophic support.

Research Summary

• Based on extensive Semax research demonstrating BDNF upregulation, combined with studies on terminal modifications that substantially improve peptide stability and biological activity.

Scientific Citations

• Dolotov, O. V., et al. (2006). Semax regulates BDNF and TrkB expression. Brain Research, 1117(1), 54–60.
• Bhattacharya, S., et al. (2012). A novel peptide (P021) inhibits tau hyperphosphorylation. Journal of Alzheimer's Disease, 31(1), 85–99.

Handling & Storage

Store unreconstituted at −20°C (LT) or 2–8°C (ST). After reconstitution, refrigerate and use within 30 days. Protect from light and moisture.

Overview

IllumiNeuro is a Longevix nootropic blend combining four neuro-active peptides: Pinealon, N-Acetyl Semax Amidate, N-Acetyl Selank Amidate and PE-22-28, each verified individually by third-party analysis.

Mechanism of Action

Semax and Selank analogues modulate BDNF expression and monoaminergic and GABAergic signalling; Pinealon is a short regulatory peptide studied for neuronal protection; PE-22-28 is a spadin-derived peptide studied for its action on TREK-1 channels.

Potential Applications

Cognitive support, focus and stress-resilience research protocols under medical supervision.

Research Summary

• Component peptides have each been studied for neurotrophic, anxiolytic or neuroprotective effects in preclinical and clinical settings.

Scientific Citations

• Dolotov, O. V., et al. (2006). Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Research, 1117(1), 54–60.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C away from direct light. Stable for 30 days post-reconstitution.

Overview

SNAP-8 is a synthetic octapeptide developed as an enhanced analogue of Argireline, primarily used in topical cosmetic formulations to reduce dynamic expression lines.

Mechanism of Action

Mimics the N-terminal region of SNAP-25, an essential component of the SNARE complex. By competitively interfering with SNARE complex formation, reduces neurotransmitters responsible for facial muscle contraction.

Potential Applications

Reduction of dynamic expression wrinkles (forehead lines, crow's feet, glabellar lines), and as a non-invasive alternative or adjunct to botulinum toxin treatments.

Research Summary

• Clinical studies on Argireline demonstrated wrinkle depth reductions of approximately 30% after 30 days. SNAP-8 developed with enhanced receptor affinity for greater efficacy.

Scientific Citations

• Blanes-Mira, C., et al. (2002). A synthetic hexapeptide (Argireline) with antiwrinkle activity. International Journal of Cosmetic Science, 24(5), 303–310.

Handling & Storage

Store at 2–8°C, protected from light. Typically remains stable for 12–24 months under recommended conditions.

Overview

GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-l-histidyl-l-lysine. It has a high affinity for copper and is heavily involved in biological healing and anti-aging processes.

Mechanism of Action

Modulates over 4,000 human genes, strongly stimulating production of collagen, elastin, and glycosaminoglycans. Heavily regulates scar tissue breakdown by modulating metalloproteinases.

Potential Applications

Skin tightening, wrinkle reduction, hair follicle stimulation (alopecia), wound healing, and post-surgical aesthetic recovery.

Research Summary

• Clinically proven to be more effective than Vitamin C and Retinoic Acid at increasing collagen synthesis in photo-aged skin.

Scientific Citations

• Pickart, L., & Margolina, A. (2018). Regenerative and Protective Actions of the GHK-Cu Peptide. International Journal of Molecular Sciences, 19(7), 1987.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Note: SQ injections can cause site pip. Stable for 30 days post-reconstitution.

Overview

GLOW is a premium, synergistic 3-peptide aesthetic and regenerative blend containing Thymosin Beta-4 (10mg), BPC-157 (10mg), and GHK-Cu (50mg). Bridges the gap between inner tissue repair and outward skin appearance.

Mechanism of Action

Combines BPC-157's rapid vascular rebuilding, TB4's cellular migration for tissue healing, and GHK-Cu's massive upregulation of collagen and elastin synthesis.

Potential Applications

Skin rejuvenation, scar reduction, soft-tissue comfort, post-surgical aesthetic recovery, and anti-aging resilience.

Research Summary

• Uniquely formulated to enhance total-body structural integrity while visibly improving skin elasticity and firmness via the high concentration of GHK-Cu.

Scientific Citations

• Proprietary blend: efficacy supported by combined clinical literature of BPC-157, TB4, and GHK-Cu.

Handling & Storage

Reconstitute with bacteriostatic water. Store at 2–8°C. Stable for approximately 30 days post-reconstitution.

Overview

Glutathione (GSH) is a naturally occurring tripeptide composed of three amino acids: cysteine, glutamic acid, and glycine. It is one of the body's major endogenous antioxidants and plays an important role in protecting cells from oxidative stress. Glutathione is present in high concentrations in the liver and is involved in cellular defense, redox regulation, and the metabolism of various compounds.

Mechanism of Action

Glutathione acts as a reducing agent and antioxidant by donating electrons to neutralize reactive oxygen species (ROS) and other reactive compounds. It also functions as a cofactor for glutathione peroxidase and participates in glutathione-S-transferase pathways involved in the metabolism and elimination of electrophilic compounds. Glutathione helps maintain cellular redox balance and supports the regeneration of other antioxidants, including vitamins C and E.

Potential Applications

Glutathione has been investigated for antioxidant and cellular protection, liver and metabolic health, oxidative-stress management, immune function, and general wellness. It has also been studied in dermatological research, particularly in relation to melanin synthesis and skin pigmentation.

Research Summary

• Research supports glutathione's fundamental role in antioxidant defense and cellular redox regulation. Studies have investigated supplementation in conditions associated with oxidative stress, including metabolic disorders, liver-related conditions, neurodegenerative disease, and immune dysfunction. Clinical evidence for supplementation varies depending on the indication, formulation, dose, and route of administration. Evidence for cosmetic and skin-lightening applications remains mixed and requires further controlled clinical research.

Scientific Citations

• Citation list for this compound is being compiled.

Handling & Storage

Supplied as Glutanex Injection (Nexus Pharma), a freeze-dried 1200mg glutathione vial for I.M. / I.V. infusion, 10 vials per box. Store in a shaded, sealed container at room temperature (1–30°C) prior to use.

Overview

Bacteriostatic Water for Injection, USP — sterile, non-pyrogenic water containing 0.9% benzyl alcohol as a bacteriostatic preservative.

Mechanism of Action

Benzyl alcohol arrests growth of potentially contaminating bacteria, allowing for repeated withdrawals from a multi-dose vial over an extended period.

Potential Applications

Diluting or dissolving lyophilized peptides and medications for subcutaneous or intramuscular injections.

Research Summary

• Standardized pharmacological solvent maintaining sterility and prolonging the half-life of reconstituted peptide vials for up to 28–30 days.

Scientific Citations

• Not applicable (Standard USP monograph item).

Handling & Storage

Store at room temperature (20–25°C). Once punctured, safe to use for 28 days before disposal.

Overview

Hospira Bacteriostatic Water for Injection, USP — a 30 mL sterile, multi-dose vial preserved with 0.9% benzyl alcohol to prevent bacterial growth and allow safe, repeated needle entry.

Mechanism of Action

The 0.9% benzyl alcohol preservative inhibits bacterial growth within the vial, allowing it to be safely accessed multiple times for different preparations without compromising sterility.

Potential Applications

Reconstitution and dilution of medications, including antibiotics, biologics, hormone therapies, and peptides — ideal when a single vial needs to be accessed multiple times for different preparations.

Research Summary

• Trusted across hospitals, clinics, compounding pharmacies, and research labs for consistent, pharmaceutical-grade reconstitution quality.

Scientific Citations

• Not applicable (standard USP monograph item).

Handling & Storage

USP Grade, sterile, and non-pyrogenic. Solvent/diluent only — contains no active therapeutic agents. Store at room temperature; follow standard multi-dose vial-in-use guidelines once punctured.

Overview

Sterile dilute acetic acid solution used as an alternative reconstitution solvent for peptides that are more stable or soluble at a slightly acidic pH.

Mechanism of Action

The mildly acidic pH improves solubility and slows aggregation and degradation of certain peptides and proteins after reconstitution.

Potential Applications

Reconstitution of IGF-1 LR3 and other peptides recommended for acidic diluent.

Research Summary

• Commonly specified as the preferred diluent for IGF-1 analogues to preserve stability in solution.

Scientific Citations

• Not applicable (standard reconstitution solvent).

Handling & Storage

Store at room temperature (20–25°C), protected from light. Once punctured, use within 28 days.